HVAC - Clean rooms?

Clean room requirements can feel intimidating when you’re just getting started, especially in medical device manufacturing where ISO 7 (10,000) and ISO 8 (100,000) standards are strict about airflow, particle counts, and pressurization. You don’t need to design the system yourself, but having a baseline understanding will help you get more out of your consultant and feel more confident working alongside your senior.

A good starting point is asking the consultant for a simple airflow diagram showing CFM, number of HEPA filters, and the pressurization cascade. Even a quick visual helps you understand why certain decisions were made. When you get the chance, ask how they calculated CFM and air changes per hour, most designs factor in ISO guidelines, occupancy, equipment heat load, and desired recovery time. For AHU selection, you can focus on the reasoning rather than the calculations: filtration stages, humidity control, temperature stability, and redundancy often drive the choice.

Since clean rooms rely heavily on proper maintenance, many facilities use specialized services like RMS Cleaning because they understand how surface contamination affects particle counts. Their local listing here: https://maps.app.goo.gl/Zc6wizZ5c1oSpfMK7, gives a good example of the type of controlled-environment support available.